Two patients get PRP in the same knee on the same day in the same city. One is back on the trail in six weeks. The other in six months. The difference has almost nothing to do with luck.
Dr. Aneesh Garg, DO, CAQ sits down with AJ Patton of Biotechnology Institute of Spain and their regenerative platform Endoret PRGF. AJ has 15 years in regenerative medicine and BTI has been pioneering research for over 30 years. Together they break down what is in the syringe, why PRP studies contradict each other, and what actually separates a great outcome from a disappointing one.
Chapters:
- 00:00 Two patients, same knee, same day. One back in six weeks, one in six months. Why?
- 01:09 AJ Patton introduction: 15 years in regenerative medicine, BTI and Endoret PRGF
- 03:18 What AJ believed about PRP when he started that he no longer believes
- 04:25 The biggest misconception doctors have about PRP
- 08:22 When blood is drawn and spun, what components actually matter?
- 10:25 Red blood cells, leukocytes, and platelets: what you want and what you do not
- 12:05 Platelets: the vessels that carry growth factors to the injury site
- 12:25 Activated vs. non-activated PRP: meta-analysis of 14 studies, 1,300 patients
- 15:39 EMTT and shockwave to prep the tissue before injection
- 16:49 Why two PRP studies can reach completely opposite conclusions
- 21:19 Leukocyte-free and fully activated: 8 to 10 day time-release growth factor delivery
- 23:24 Landmark guidance hits the mark only 25% of the time
- 25:48 The acupuncturist doing PRP: why training and experience matter
- 28:46 Are you in the outcomes business or the revenue business?
- 35:54 Ask the clinic: tell me a time you said no, this is not going to work
- 43:57 AJ’s personal case: meniscus tear healed with PRP instead of surgery
- 46:42 Where is regenerative medicine going in the next five years?
- 49:02 Why shockwave and PRP together outperform either alone
- 54:32 Intraosseous injections for knee arthritis and intraneural injections for nerve damage
- 57:55 The label does not tell you what you are getting. The protocol does.
